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End-to-end workflow

analyze_dose_response()
Run the complete microbial dose-response analysis

Data import

as_dose_response()
Standardize grouped dose-response data
read_dose_response()
Read grouped dose-response data

Trend test

dose_trend_test()
Pre-screen for an increasing dose-response trend

Model fitting

fit_dose_response()
Fit a mechanistic dose-response model
fit_dose_response_models()
Fit a set of dose-response models

Model response functions

exponential_response()
Evaluate an exponential dose-response model
beta_poisson_response()
Evaluate an approximate beta-Poisson dose-response model
exact_beta_poisson_response()
Exact beta-Poisson dose-response function
exact_beta_poisson_survival()
Exact beta-Poisson survival function
effective_dose()
Calculate an effective dose
prediction_curve()
Create prediction curves and bootstrap intervals

Diagnostics, comparison, and assessment

goodness_of_fit()
Goodness-of-fit statistics
compare_dose_response_models()
Compare fitted dose-response models
assess_dose_response_models()
Assess fitted dose-response models
consensus_model_decision()
Experimental consensus model decision

Bootstrap uncertainty

bootstrap_dose_response()
Bootstrap a fitted dose-response model
bootstrap_dose_response_async()
Start a non-blocking dose-response bootstrap
bootstrap_dose_response_models()
Bootstrap both dose-response models
collect_bootstrap()
Collect a non-blocking bootstrap job
bootstrap_confint()
Bootstrap percentile confidence intervals

broom / tidymodels methods

tidy(<qdr_fit>)
Tidy a dose-response fit
glance(<qdr_fit>)
Glance at a dose-response fit
augment(<qdr_fit>)
Augment dose-response data with fitted values

Pooling multiple datasets

poolability_test()
Test whether dose-response datasets are statistically poolable
poolability_combinations()
Report poolability for every combination of datasets
group_datasets()
Group dose-response datasets into mutually poolable sets

Plotting

plot_dose_response()
Plot a fitted dose-response model
plot_model_overlay()
Overlay fitted models on one dose-response plot

Data

ward_rotavirus
Ward rotavirus human-challenge dose-response data